Discontinue use if severe skin reactions occur. Known G6PD deficiency; glutathione depleted eg, eating disorders, cystic fibrosis, HIV infection, starvation, cachexia. Not to be taken concomitantly w/ other paracetamol-containing medicines. Long-term use w/ carbamazepine, phenobarb, phenytoin, primidone, rifampicin, St. John's wort or other drugs inducing liver enzymes. Alcoholic hepatic disease; hepatotoxicity. Pregnancy & lactation. Not recommended in childn <1 mth.
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